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Laboratory

Research subjects

1. Research for polyamine regulating protein “Antizyme”( What is “Antizyme” ?
 (1)Tumor growth and ubiquitin-independent degradation of Myc proteins mediated by antizyme 2
 (2)Identification of antizyme 1- and antizyme 2-interacting proteins and their function
 (3)Regulatory mechanism of ATP-citrate lyase by antizyme
 (4)Mechanism of polyamine-induced translational frameshifting of antizyme mRNA

2. Function and medical application of polyamines
 (1)Analyses for physiological functions of polyamines
 (2)Analyses of polyamine effects on the translation regulation
 (3)Application of polyamines on medical diagnosis
 (4)Polyamines and cancer: Urinary diacetylspermine as a tumor marker
 (5)Analyses of polyamine effects on RNA structure by using RNA aptamer


History of the Department

1975
Professor Shin-ichi Hayashi was nominated as the Chair of Department of Nutrition
1995
Department name was changed to "Department of Biochemistry 2"
2007
Department name was changed to "Department of Molecular Biology"
Professor Matsufuji was nominated as the Chair


バナースペース

Department of Molecular Biology The Jikei University School of Medicine

3-25-8, Nishi-shinbashi
Minato-ku, Tokyo
105-8461, Japan

Phone: +81-3-3433-1111 ext. 2275
Fax: +81-3-3436-3897