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東京慈恵会医科大学・分子生物学講座
研究業績
研究業績
Publications
Yogosawa S,
Ohkido M
, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K.
Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient.
Commun Biol.
2021; 4(1): 1204
Li Y,
Tajima A
, Mattie FJ, Green MH, Ross AC.
Pregnancy and lactation alter Vitamin A metabolism and kinetics in rats under Vitamin A adequate dietary conditions
.
Nutrients.
2021; 13(8): 2853
Oguro A
, Shigeta T, Machida K, Suzuki T, Iwamoto T,
Matsufuji S
, Imataka H.
Transalation efficiency affects the sequence-independent + 1 ribosomal frameshifting by polyamines.
J Biochem.
Aug 1st 2020;
168
(2):139-49.
doi: 10.1093/jb/mvaa032. PMID: 32181810
Murai N
.
Ubiquitin-independent proteasomal degradation mediated by antizyme.
Book chapter published 2020; In Zhan X ed.
Ubiquitin Proteasome Pathway.
IntechOpen. June 4th 2020;
doi:10.5772/intechopen.92623
Katagiri S, Hosono K, Hayashi T,
Murai N
, Wake E, Miyata I, Mizobuchi K, Kurata K, Matsuura T, Nakano T, Hatta Y.
Novel biallelic splice-site BBS1 variants in Bardet-Biedle syndrome: a case report of the first Japanese patient.
Doc Ophthalmol.
2020 Aug;
141
(1):77-88.
doi: 10.1007/s10633-020-09752-5. Epub 2020 Jan 29.; PMID: 31997113
Fujimi TJ, Mezaki Y, Masaki T,
Tajima A
, Nakamura M, Yoshikawa A,
Murai N
, Aizawa M, Kojima S, Matsumoto Y, Aizaki H, Matsuura T.
Investigation of the effects of urea cycle amino acids on the expression of ALB and CEBPB in the human hepatocellular carcinoma cell line FLC-4.
Hum Cell.
2020 Jul;
33
: (3):590-8.
doi: 10.1007/s13577-020-00383-1. Epub 2020 May 30. PMID: 32474770
Ohta R,
Oguro A
, Nishimura K, Murai K, Fujioka H, Arisawa M.
Design and synthesis of
N
1
,
N
8
-diacetylspermidine analogues having a linker with desired functional groups.
Organic & Biomolecular Chemistry.
2019;
17
(4): 867-87
doi: 10.1039/c8ob02900h. PMID: 30628612
Tamari K, Konno M, Asai A, Koseki J, Hayashi K, Kawamoto K,
Murai N
,
Matsufuji S
, Isohashi F, Satoh T, Goto N, Tanaka S, Doki Y, Mori M, Ogawa K, Ishii H.
Polyamine flux suppresses histone lysine demethylases and enhances ID1 expression in cancer stem cells.
Cell Death Discov.
2018;
4
:104.
PMID: 30455990
Katagiri S, Hayashi T, Yoshitake K,
Murai N
, Matsui Z, Kubo H, Satoh H,
Matsufuji S
, Takamura T, Yokoo T, Omori Y, Furukawa T, Iwata T, Nakano T.
Compound heterozygous splice site variants in the SCLT1 gene highlight an additional candidate locus for Senior-Loken syndrome.
Sci Rep.
2018 Nov;
138
(1):16733.
doi: 10.1038/s41598-018-35152-6. PMID: 30425282
Yamamoto Y, Makino T, Kudo H, Ihn H,
Murakami Y
,
Matsufuji S
, Fujiwara K, Shin M.
Expression and distribution patterns of spermine, spermidine, and putrescine in rat hair follicle.
Histochem Cell Biol. 2018; 149(2): 161-7.
PMID: 29445227
Murai N
,
Murakami Y
,
Tajima A
,
Matsufuji S
.
Novel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 2.
Sci. Rep.
2018;
8
(1): 3005.
PMID: 29445227
Oguro A
, Yanagida A, Fujieda Y, Amano R, Otsu M, Sakamoto T, Kawai G,
Matsufuji S
.
Two stems with different characteristics and an internal loop in an RNA aptamer contribute to spermine-binding.
J Biochem.
2017;
161
: 197-206.
PMID: 28173167
Jaafar ZA,
Oguro A
, Nakamura Y, Kieft JS.
Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling.
eLife.
2016;
5
: e21198.
PMID: 28009256
Tajima A
,
Murai N
,
Murakami Y
, Iwamoto T, Migita T,
Matsufuji S
.
Polyamine regulating protein antizyme binds to ATP citrate lyase to accelerate acetyl-CoA production in cancer cells.
Biochem Biophys Res Commun. 2016; 471(4): 646-51.
PMID: 26915799
Murai N
.
Antizyme.
In Kusano T, Suzuki H, editors.
Polyamines, a universal molecular nexus for growth, survival and specialized metabolism.
New York: Springer; 2015: 91-9.
Murakami Y
,
Ohkido M
,
Takizawa H
,
Murai N
,
Matsufuji S
.
Multiple forms of mouse antizyme inhibitor 1 mRNA differentially regulated by polyamines.
Amino Acids.
2014;
46
(3): 575-83.
PMID: 24077669
Matoba K
, Kawanami D, Tsukamoto M, Kinoshita J, Ito T, Ishizawa S, Kanazawa Y, Yokota T,
Murai N
,
Matsufuji S
, Utsunomiya K.
Rho-kinase regulation of TNF-alpha-induced nuclear translocation of NF-kappaB Re1A/p65 and M-CSF espression via p38 MAPK in mesangial cells.
Am J Physiol Renal Physiol.
2014;
307
: F571-80.
PMID: 25007875
Hirata Y
,
Murai N
, Yanaihara N, Saito M, Saito M, Urashima M,
Murakami Y
,
Matsufuji S
, Okamoto A.
MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma.
BMC Cancer.
2014 ;
14
: 799.
PMID: 25366985
Matoba K
, Kawanami D, Okada R, Tsukamoto M, Kinoshita J, Ito T, Ishizawa S, Kanazawa Y, Yokota T,
Murai N
,
Matsufuji S
, Takahashi-Fujigasaki J, Utsunomiya K.
Rho-kinase inhibition prevents the progression of diabetic nephropathy by downregulating hypoxia-inducible factor 1alpha.
Kidney Int.
2013 ;
84
: 545-54.
PMID: 23615507
Murai N
,
Murakami Y
,
Matsufuji S
.
Protocols for studying antizyme expression and function.
Methods Mol Biol.
2011;
720
: 237-67.
PMID: 21318878
Ivanov IP,
Matsufuji S
.
Autoregulatory frameshifting in antizyme gene expression governs polyamine levels from yeast to mammals.
In: Atkins JF, Gesteland RF, editors.
Recording: Nucleic Acids and Molecular Biology 24.
New York: Springer; 2010: 281-300.
Murai N
,
Shimizu A
,
Murakami Y
,
Matsufuji S
.
Subcellular localization and phosphorylation of antizyme 2.
J Cell Biochem.
2009;
108
(4): 1012-21.
PMID: 19725046
Horiya S
, Inaba M, Koh CS, Uehara H, Masui N, Mizuguchi M, Ishibashi M,
Matsufuji S
, Harada K.
Replacement of the lambda boxB RNA-N peptide with heteros RNA-peptide interactions relaxes the strict spatial requirements for the formation of a transcription anti-termination complex.
Mol Microbiol.
2009;
74
(1): 85-97.
PMID: 19708917
Murakami Y
, Suzuki J, Samejima K, Kikuchi K, Hascilowicz T,
Murai N
,
Matsufuji S
, Oka T.
The change of antizyme inhibitor expression and its possible role during mammalian cell cycle.
Exp Cell Res.
2009;
315
: 2301-11.
PMID: 19426728.
Oguro A
, Ohtsu T, Nakamura Y.
An aptamer-based biosensor for mammalian initiation factor eukaryotic initiation factor 4A.
Anal Biochem.
2009;
388
(1): 102-7.
PMID: 19250914.
Liao CP, Lasbury ME, Wang SH, Zhang C, Durant PJ,
Murakami Y
,
Matsufuji S
, Lee CH.
Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages.
J Biol Chem.
2009;
284
(12): 8174-84.
PMID: 19158080
Tang H, Ariki K,
Ohkido M
,
Murakami Y
,
Matsufuji S
, Li Z, Yamamura K.
Role of ornithine decarboxylase antizyme inhibitor in vivo.
Genes Cells.
2009;
14
(1): 79-87.
PMID: 19077035
Horiya S
, Koh CS,
Matsufuji S
, Harada K.
Analysis of the interaction between selected RNA-binding peptides and a target RNA containing a bulge and a GNRA-type tetraloop.
Nucleic Acids Symp Ser (Oxf).
2008; (52): 209-10.
PMID: 18776327
Namy O, Galopier A, Martini C,
Matsufuji S
, Fabret C, Rousset JP.
Epigenetic control of polyamines by the prion [PSI(+)].
Nat Cell Biol.
2008;
10
(9): 1069-75.
PMID: 19160487
Isome M, Lortie MJ,
Murakami Y
, Parisi E,
Matsufuji S
, Satriano J.
The antiproliferative effects of agmatine correlate with the rate of cellular proliferation.
Am J Physiol Cell Physiol.
2007;
293
(2): C705-11.
PMID: 17475661
Kosuge M
,
Takizawa H
, Maehashi H, Matsuura T,
Matsufuji S
.
A comprehensive gene expression analysis of human hepatocellular carcinoma cell lines as components of a bioartificial liver using a radial flow bioreactor.
Liver Int.
2007;
27
(1): 101-8.
PMID: 17241388
Yamaguchi Y, Takatsuka Y,
Matsufuji S
,
Murakami Y
, Kamio Y.
Characterization of a counterpart to Mammalian ornithine decarboxylase antizyme in prokaryotes.
J Biol Chem.
2006;
281
(7): 3995-4001.
PMID: 16354653
Watanabe M, Konishi M,
Ohkido I
,
Matsufuji S
.
Enhanced sodium-dependent extrusion of magnesium in mutant cells established from a mouse renal tubular cell line.
Am J Physiol Renal Physiol.
2005;
289
(4): F742-8.
PMID: 15886276
Nakamatsu Y
,
Matsufuji S
.
Selection of translational frameshift signals in E. coli.
Jikeikai Med J.
2004;
51
(4): 113-21.
Higashi K, Yoshida K, Nishimura K, Momiyama E, Kashiwagi K,
Matsufuji S
, Shirahata A, Igarashi K.
Structural and functional relationship among diamines in terms of inhibition of cell growth.
J Biochem (Tokyo).
2004;
36
(4): 533-9.
PMID: 15625324
Shinoda M, Tanaka Y, Kuno T, Matsufuji T,
Matsufuji S
,
Murakami Y
, Mizutani T.
High levels of autoantibodies against drug-metabolizing enzymes in SLA/LP-positive AIH-1 sera.
Autoimmunity.
2004;
37
(6-7): 473-80.
PMID: 15621574
Matveeva OV, Foley BT, Nemtsov VA, Gesteland RF,
Matsufuji S
, Atkins JF, Ogurtsov AY, Shabalina SA.
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides: application to HIV genome.
BMC Bioinformatics.
2004;
5
: 44.
PMID: 15115544
Karamysheva ZN
, Karamyshev AL, Ito K, Yokogawa T, Nishikawa K, Nakamura Y,
Matsufuji S
.
Antizyme frameshifting as a functional probe of eukaryotic translational termination.
Nucleic Acids Res.
2003;
31
(20): 5949-56.
PMID: 14530443
Murai N
,
Murakami Y
,
Matsufuji S
.
Identification of nuclear export signals in antizyme-1.
J Biol Chem.
2003;
278
(45): 44791-8.
PMID: 12941943
Yanaihara N
, Okamoto A,
Matsufuji S
.
A commonly deleted region in ovarian cancer on chromosome 19p13.3, not including the OAZ1 gene.
Int J Oncol.
2003;
23
(3): 567-75.
PMID: 12888889
Hascilowicz T
,
Murai N
,
Matsufuji S
,
Murakami Y
.
Regulation of ornithine decarboxylase by antizymes and antizyme inhibitor in zebrafish (Danio rerio).
Biochim Biophys Acta.
2002;
1578
(1-3): 21-8.
PMID: 12393184
Atkins JF, Baranov PV, Fayet O, Herr AJ, Howard MT, Ivanov IP,
Matsufuji S
, Miller WA, Moore B, Prére MF, Wills NM, Zhou J, Gesteland RF.
Overriding standard decoding: implications of recoding for ribosome function and enrichment of gene expression.
Cold Spring Harb Symp Quant Biol.
2001;
66
: 217-32.
PMID: 12762024
Howard MT, Shirts BH, Zhou J, Carlson CL,
Matsufuji S
, Gesteland RF, Weeks RS, Atkins JF.
Cell culture analysis of the regulatory frameshift event required for the expression of mammalian antizymes.
Genes Cells.
2001;
6
(11): 931-41.
PMID: 11733031
Chattopadhyay MK
,
Murakami Y
,
Matsufuji S
.
Antizyme regulates the degradation of ornithine decarboxylase in fission yeast Schizosaccharomyces pombe. Study in the spe2 knockout strains.
J Biol Chem.
2001;
276
(24): 21235-41.
PMID: 11283013
Kim LK, Matsufuji T,
Matsufuji S
, Carlson BA, Kim SS, Hatfield DL, Lee BJ.
Methylation of the ribosyl moiety at position 34 of selenocysteine tRNA[Ser]Sec is governed by both primary and tertiary structure.
RNA.
2000;
6
(9): 1306-15.
PMID: 10999607
Ivanov IP,
Matsufuji S
,
Murakami Y
, Gesteland RF, Atkins JF.
Conservation of polyamine regulation by translational frameshifting from yeast to mammals.
EMBO J.
2000;
19
(8): 1907-17.
PMID: 10775274
Murakami Y
,
Matsufuji S
,
Hayashi S
, Tanahashi N, Tanaka K.
Degradation of ornithine decarboxylase by the 26S proteasome.
Biochem Biophys Res Commun.
2000;
267
(1): 1-6. Review.
PMID: 10623564
Saito T
,
Hascilowicz T
,
Ohkido I
,
Kikuchi Y
, Okamoto H,
Hayashi S
,
Murakami Y
,
Matsufuji S
.
Two zebrafish (Danio rerio) antizymes with different expression and activities.
Biochem J.
2000;
345
Pt 1: 99-106.
PMID: 10600644
日本語論文・著書
村井 法之
.ヒトの細胞と分子基盤 細胞の発生.翻訳.In 栗原敏(監修)リッピンコットシリーズ
イラストレテッド統合臨床基礎医学.
2018: 1-7. 医学書院.
村井 法之
.アンチザイム(シリーズ ポリアミン研究).
日本ポリアミン学会.
2017;
4
(1): 8-13.
大城戸 真喜子
.「次世代を育てる」医学生・看護学生への試み〜ロービジョン者の抱える問題に気づき 、想像し 、解決する方法を考える機会としてのロービジョン教育〜.
眼科臨床紀要
.2016;
9
: 113-9.
松藤 千弥
.研究はなんのためにあるのだろう.In 栗原敏(監修)
医療入門.
2006: 122-128. 医学書院.
松藤 千弥
.拡がりをみせる細胞遺伝子のリコーディング.
実験医学別冊.
実験医学別冊.
2004;
22
(17) : 2461-2468. 羊土社.
松藤 千弥
,稲田利文.ゲノムからみた翻訳とRNAの品質管理.
ゲノム医学.
2004;
4
(4): 377-383. メジカルレビュー社.
松藤 千弥
.タンパク質生合成.In 中村義一編.
RNAがわかる.
2003: 59-69. 羊土社.
村上 安子
,
松藤 千弥
.迅速なポリアミン制御を可能にするオルニチン脱炭酸酵素の分解系.
化学と生物.
2001;
39
(3): 171-176.
村上 安子
,
松藤 千弥
.オルニチン脱炭酸酵素とアンチザイム.
実験医学.
2001;
19
(2): 173−179.
松藤 千弥
,藤原 俊伸,中村 義一.リコーディング.In 志村令郎,渡辺公綱編.
RNA研究の最前線.
2000: 139−144. シュプリンガー・フェアラーク東京,東京.
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学校法人 慈恵大学
日本ポリアミン学会
東京慈恵会医科大学・分子生物学講座
〒105-8461
東京都港区西新橋3-25-8 F棟1階
TEL 03-3433-1111 (内)2276
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